Gewebeproben unter dem Mikroskop

Generative AI in Pathology: Artificial Histological Skin Samples

In today’s blog post, we are excited to introduce you to a fascinating development in the field of pathology – the use of generative artificial intelligence (AI) to create artificial histological images of skin samples. This technology opens up new perspectives for medical research and diagnosis, similar to examples in other areas such as ChatGPT for text or Stable Diffusion for artistic photos.

What is Generative AI?

Generative AI is an exciting form of artificial intelligence that aims to generate new data similar to what it has seen during training. It utilizes artificial neural networks to learn from existing datasets and generate new, similar data based on that knowledge. In other AI domains, like ChatGPT, such technologies are used to create natural language text.

Creating Artificial Histological Skin Samples

Generative AI opens a fascinating new chapter in pathology by enabling the creation of artificial histological images of skin samples. During training, the artificial neural network is fed a variety of real histological skin images. It learns the characteristics, patterns, and structures present in the genuine samples and uses this knowledge to generate new images with similar properties.

Example: Simulated BCC growth. Our generative AI can also simulate intermediate shapes of two segmentation masks. Thus, it is possible to visualize how the AI model imagines the steps from BCC-free tissue (left) to an ever-growing BCC region (right).

Applications of Artificial Histological Images

  1. Research and Education: Artificial histological images are invaluable in medical research and education. They provide an almost endless source of examples for various skin diseases and conditions, allowing medical students and researchers to learn and improve their diagnostic skills.
  2. Data Enrichment: Generative AI can contribute to expanding datasets in pathology. By generating artificial histological images, data volumes can be increased, supporting the development and improvement of AI algorithms for the detection of skin diseases.
  3. Development of New Diagnostic Methods: Artificial histological images facilitate the simulation and validation of new diagnostic methods and algorithms. Pathologists can use their expertise to review and enhance these procedures.
  4. Anonymous Data for Knowledge Sharing: Artificial histological images can be used in anonymized form for knowledge exchange between pathologists and medical institutions. This encourages collaboration and progress in the diagnosis and treatment of skin diseases.

Advantages for the Pathologist

While generative AI offers valuable opportunities, it is essential to emphasize that the pathologist continues to play an irreplaceable role in diagnosing and treating patients. Artificial histological images serve as a complement and support, but they do not replace the knowledge and expertise of an experienced pathologist.


The use of generative AI to create artificial histological skin samples promises an exciting future for pathology. From medical research to improved diagnostic capabilities, this technology offers numerous benefits for pathologists and patients alike. We look forward to witnessing further advancements in this thrilling area and will continue to drive innovative solutions.

Similar Posts